Toltrazuril Dosage Calculator for Rabbits [Updated on: 01/10/26 05:31]
       Toltrazuril is a broad-spectrum anticoccidial drug that is effective against both gamont & schizont stages of Eimeria spp. It's used to treat coccidia in rabbits and sold as Baycox in most part of the world. Unfortunately toltrazuril is not readily available in the US. Ponazuril (toltrazuril sulfone, the alternate chemical name for ponazuril) is an active metabolite of toltrazuril and is used. Ponazuril is sold by Merial as Marquis to treat EPM in horses in the US. Note: The bioavailability of toltrazuril and ponazuril are different and must be dose and treated as different drugs!

       There are a number different treatment protocols currently for rabbits both with amounts and times given. Dr. Esther van Praag of Medirabbit recommends a 9 day dosing protocol (2 days on, 5 days off, 2 days on) dosing at 15 mg/kg with toltrazuril 5% (50 mg/mL).

       There are other concentrations of toltrazuril (2.5% and 10%) but 5% is most commonly used with rabbits. If you have any questions please talk to your rabbit-savvy vet! The calculator will only show the dosing based on the data inputted. Normally Toltrazuril comes in large quantities to treat animals such as horses and can be hard to find small amounts... All Things Bunnies (US) sells small amounts for rabbits, it's a 5% suspension found here. NOTE: in 2024 the FDA forced All Things Bunnies to stop selling this product because: "... unapproved new animal drug, and introducing or delivering this product for introduction into interstate commerce is prohibited under section 301(a) of the FD&C Act [21 U.S.C. § 331(a)]."

        NOTE: The suggested dose of 25 mg/kg given in some texts for toltrazuril (possibly as a mistranslation/miscalculation from 25 ppm in drinking water) is too high and has anecdotally been associated with anorexia and decreased production of faeces. From "Rabbits Coccidiosis - Are you missing it?" by Redrobe, S. (Rabbit Health Matters, Chilwell, UK, 28 February 2009).

Calculate dosing
Dosage in mg/kg: mg/kg
Rabbit's weight kg lbs  kg

Enter values & click calculate ↵
1 mL, mls, or ml (milliliter) = 1 cc or cc³ (cubic centimeter)
"≈" = "almost equal to"
1 kg = 2.20462262185 lbs
$$ \frac{ 15 \text{ mg/kg} \times 2.26 \text{ kg} }{ 50 \text{ mg/mL} } = 0.678 \text{ mL} $$
[33.9 mg ÷ 4.98 lbs = 6.8 mg/lb ≈ 6.8 mg/lb]

Nine day dosing protocol
2 days on, 5 days off, 2 days on
Using a 5% suspension
Day Dose
1 0.68 mL [mls] PO [orally]
2 0.68 mL [mls] PO [orally]
3 → 7 0̸
8 0.68 mL [mls] PO [orally]
9 0.68 mL [mls] PO [orally]
Nine day dosing protocol
2 days on, 5 days off, 2 days on
Using a 2.5% suspension
Day Dose
1 1.36 mL [mls] PO [orally]
2 1.36 mL [mls] PO [orally]
3 → 7 0̸
8 1.36 mL [mls] PO [orally]
9 1.36 mL [mls] PO [orally]
Nine day dosing protocol
2 days on, 5 days off, 2 days on
Using a 10% suspension
Day Dose
1 0.34 mL [mls] PO [orally]
2 0.34 mL [mls] PO [orally]
3 → 7 0̸
8 0.34 mL [mls] PO [orally]
9 0.34 mL [mls] PO [orally]

       Dr. Esther van Praag (Medirabbit) current recommended treatment is 2 days on, 5 days off, 2 days on at 15 mg/kg with toltrazuril 5% (50 mg/mL). On her webpage she has a older protocol of "twice, repeat after 5 days" using 2.5 to 5 mg/kg using toltrazuril [Baycox®]. 2016

       The Textbook of Rabbit Medicine (edition 1 & 2) recommends 25 mg/kg PO [orally] 2 days on, 5 days off, 2 days on. DW (distilled water). 2014

       Dr. Dana Krempels recommends "20mg/kg Q 24 hours" for ponazuril/toltrazuril. Her own data shows complete parasite eradication in three days of treatment with ponazuril (Marquis). 2007
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[Updated on: 01/10/26 05:31]