Megacolon Research Papers [Updated on: 05/14/15 03:52]

This information is for reference only! See a rabbit savvy Vet if you need help with your rabbit! PLEASE NOTE!! The "Research Paper" section below has information and links to REAL RESEARCH PAPERS. Rabbits were breed and put down to study Megacolon and the effect the En gene has on them. They can include necropsy (autopsy) pictures. The language and images may upset some.

• 2014; "The KIT Gene Is Associated with the English Spotting Coat Color Locus and Congenital Megacolon in Checkered Giant Rabbits (Oryctolagus cuniculus)"
  Luca Fontanesi, Manuela Vargiolu, Emilio Scotti, Rocco Latorre, Maria Simonetta Faussone Pellegrini, Maurizio Mazzoni, Martina Asti, Roberto Chiocchetti, Giovanni Romeo, Paolo Clavenzani, Roberto De Giorgi, Published: April 15, 2014, PLoS ONE 9(4): e93750. DOI: 10.1371/journal.pone.0093750. Research paper (local copy PDF-3.1MB)

• 2014(?); Gut flora comparison for rabbit nutrition book
  After the 2014 HRS Educational Conference (Taking Rabbit Knowledge to a Higher Level, September 27-28 hosted by the St. Louis House Rabbit Society), Christie Taylor (HRS Nationally Licensed Educator) posted about how Susan Smith, Ph.D. (helps run the Wisconsin HRS chapter), "is collecting samples from US megacolon rabbits for analysis. She's hoping to compare their gut flora to the microbes normally present in non-MC rabbits and to aid clinicians in creating therapies for MC bunns based on those results." This may be for the book on rabbit nutrition she is working on currently.

• 2010; "Endothelin receptor B (EDNRB) is not the causative gene of the English spotting locus in the domestic rabbit (Oryctolagus cuniculus)."
  Luca Fontanesi, Manuela Vargiolu, Emilio Scotti, Maurizio Mazzoni, Paolo Clavenzani, Roberto De Giorgio, G Romeo, Vincenzo Russo Published in Animal genetics 2010, DOI:10.1111/j.1365-2052.2010.02084.x. [Abstract];

• 1995; "Pathophysiological and functional aspects of the megacolon-syndrome of homozygous spotted rabbits."
  by Böderek D, Türk O, Lovén E, Wieberneit D, Wegner W. (1995) from Institute of Animal Breeding and Genetics, Hannover School of Veterinary Science, Germany., Zentralbl Veterinarmed A. 1995 Nov;42(9):549-59. doi: 10.1111/j.1439-0442.1995.tb00410.x [Abstract]; Research paper (local copy: PDF 4.7MB)

• 1995; "Albino Rabbits Can Suffer From Megacolon-Syndrome When They Are Homozygous For The 'English Spot' Gene (En/En)"
  by Wieberneit D. and Wegner W. (1995) of the Institute of Animal Breeding and Genetics, Hannover School of Veterinary Science, Germany. Published in the World Rabbit Science 1995, 3(1), p. 19-26. doi: 10.4995/wrs.1995.236 Research paper (local copy: PDF 3.1MB)

• The Problems of Spotted Breeds of Rabbits
  • 1991; "1. Fattening and body condition at slaughter, organ parameters"
    by Wieberneit D, Mahdi N, Zacharias K, Wegner W. (1991) Dtsch Tierärztl Wochenschr. 1991 Sep;98(9):352-4. [Abstract]

  • 1992; "2. Further results on the variation of characteristics in fattening and breeding animals"
    by Mahdi N, Wieberneit D, Wegner W. (1991) Dtsch Tierärztl Wochenschr. 1992 Mar;99(3):111-3. [Abstract]

  • 1993; "3. Variability of the pigmentation grade, ganglionic intestinal wall supply, relationship to pathogenesis--animal breeding and animal welfare aspects"
    by Gerlitz S, Wessel G, Wieberneit D, Wegner W. (1993) Dtsch Tierärztl Wochenschr. 1993 Jun;100(6):237-9. [Abstract]

  • 1994; "4. Morpho- and histometric findings in the CNS and thyroid glands and the hormone content in blood at slaughter of hybrid rabbits, and estimation of the heterosis effect"
    by Flemming K, Kühnel C, Wieberneit D, Wegner W. (1994) Dtsch Tierärztl Wochenschr. 1994 Nov;101(11):434-9. [Abstract]

• 1995; "A striking malformation in a spotted rabbit"
  by Wieberneit D (1995), Published November 1st, 1993 by DTW. Deutsche Tierärztliche Wochenschrift [Info]

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